Publikationen
2026
Zhang, H., Guo, Y., Adhikari, B. et al. (2026) Minute-scale control of ubiquitin-mediated degradation reveals dynamics of bacterial secreted effector-functions. Nat Commun 17, 4420. https://doi.org/10.1038/s41467-026-73213-x
Faris R., Koch R., McCaslin P., Challagundla N., Steiert B., Andersen S. E., McCullough A., Smith P., Jabeena C. A., Yau P., Rudel T, Weber M. M. (2026). The Chlamydia trachomatis-secreted effector protein CT181 binds to Mcl-1 and prolongs neutrophil survival. mBio 0:e00357-26. https://doi.org/10.1128/mbio.00357-26
Akash A, B. J., Liang C, Zarnack K and Dandekar T. (2026) RNA motifs, RNA structure, and motif context analyzed by RNAanalyzer. Nucleic Acids Research. https://doi.org/10.1093/nar/gkag392
Hovhannisyan, P., & Rudel, T. (2026). Epithelial polarity: A key player in Chlamydia trachomatis–host interactions. Microlife, uqag016. https://doi.org/10.1093/femsml/uqag016
Silvestre-Roig, C., Chevre, R., Farjia, M., Bender, A., Vocking, L. M., Richter, M., Hageb, A., Suerdieck, V., Arenas Cerro, F. J., Braster, Q., Guzman, M., Sintes, J., Sharma, S., Lemnitzer, P., Tulotta, C., Borgeling, Y., Herrero-Cervera, A., Flueter, H., Reinartz Groba, S. N.,…Soehnlein, O. (2026). Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense. Sci Immunol, 11(118), eadw7077. https://doi.org/10.1126/sciimmunol.adw7077
Thomann, S., Hemmer, H., Agrawal, A., Basu, S., Schaf, J., Vornberger, N., Krammer, T., Sagar, Imdahl, F., Poth, T., Toth, M., Zielinski, C. E., Poch, T., Krause, J., Rosenwald, A., Breitkopf-Heinlein, K., Rahbari, N., & Grun, D. (2026). An immunobiliary single-cell atlas resolves crosstalk between type 2 conventional dendritic cells and gammadelta T cells in cholangitis. Nat Commun, 17(1). https://doi.org/10.1038/s41467-026-71537-2
Gonther, S., Thieme, M., Gubert, G. F., Schilf, P., Derenda-Hell, A., Murthy, S., Hirose, M., Vaeth, M., & Sadik, C. D. (2026). Moxifloxacin Inhibits Neutrophil Responses to Immune Complexes and Ameliorates Skin Inflammation in a Model of Pemphigoid Diseases. FASEB J, 40(4), e71586. https://doi.org/10.1096/fj.202503040RR
2025
Aintablian, A., Arold, A. M., Alattar, H., Cyran, L., Schoen, C., Du Plessis, N., Walzl, G., Schaible, U., Beilhack, A., Nieuwenhuizen, N. E., & Lutz, M. B. (2025). MDSC depletion during immunization with heat-killed Mycobacterium tuberculosis increases protection against BCG infection. Front Immunol, 16, 1646526. https://doi.org/10.3389/fimmu.2025.1646526
Alzheimer, M., Froschauer, K., Svensson, S. L., Konig, F., Hopp, E., Drobnic, T., Henderson, L. D., Ribardo, D. A., Hendrixson, D. R., Bischler, T., Beeby, M., & Sharma, C. M. (2025). Functional genomics of Campylobacter -host interactions in an intestinal tissue model reveals a small lipoprotein essential for flagellar assembly. bioRxiv. https://doi.org/10.1101/2025.04.02.646747,Functional genomics of Campylobacter-host interactions in an intestinal tissue model reveals a small lipoprotein essential for flagellar assembly
Bornet, E., Prezza, G., Cecchino, L., Jenniches, L., Behrends, J., Tawk, C., Huang, K. C., Strowig, T., Vogel, J., Barquist, L., Saliba, A. E., & Westermann, A. J. (2025). Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium. Cell Rep, 44(6), 115844. https://doi.org/10.1016/j.celrep.2025.115844
Caliskan, A., Crouch, S. A. W., Pereira, J. G. N., Dandekar, T., Dandekar, G., & Breitenbach, T. (2025). Mathematical strategies for predicting resistant subpopulations from scRNAseq data of a PANC-1 3D tissue model: Insight into gemcitabine resistance and TGFB1-induced invasion and EMT. Comput Struct Biotechnol J, 27, 4476-4495. https://doi.org/10.1016/j.csbj.2025.10.032
Caliskan, D., Caliskan, A., Dandekar, T., & Breitenbach, T. (2025). gSELECT: A novel pre-analysis machine-learning library enabling early hypothesis testing and predictive gene selection in single-cell data. Comput Struct Biotechnol J, 27, 3510-3527. https://doi.org/10.1016/j.csbj.2025.07.047
Chan, A. S., Greiner, J., Marschhauser, L., Brennan, T. A., Perez-Feliz, S., Agrawal, A., Hemmer, H., Sinning, K., Cheung, J. W. L., Iqbal, Z., Klesen, A., Vico, T. A., Aprea, J., Hilgendorf, I., Seidel, T., Vaeth, M., Rog-Zielinska, E. A., Kohl, P., Schneider-Warme, F., & Grun, D. (2025). Spatiotemporal dynamics of the cardioimmune niche during lesion repair. Nat Cardiovasc Res, 4(11), 1550-1572. https://doi.org/10.1038/s44161-025-00739-6
Clavel, T., Faber, F., Groussin, M., Haller, D., Overmann, J., Pauvert, C., Poyet, M., Selkrig, J., Stecher, B., Typas, A., Vehreschild, M., Westermann, A. J., Wylensek, D., & Maier, L. (2025). Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research. Nat Biotechnol, 43(6), 878-888. https://doi.org/10.1038/s41587-025-02660-6
Cosi, V., Jung, J., Popella, L., Ponath, F., Ghosh, C., Barquist, L., & Vogel, J. (2025). An antisense oligomer conjugate with unpredicted bactericidal activity against Fusobacterium nucleatum. mBio, 16(6), e0052425. https://doi.org/10.1128/mbio.00524-25
Ehlers, G., Todtmann, A. M., Holsten, L., Willers, M., Heckmann, J., Schoning, J., Richter, M., Heinemann, A. S., Pirr, S., Heinz, A., Dopfer, C., Handler, K., Becker, M., Buchel, J., Wockel, A., von Kaisenberg, C., Hansen, G., Hiller, K., Schultze, J. L.,…Viemann, D. (2025). Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth. Nat Commun, 16(1), 2239. https://doi.org/10.1038/s41467-025-57357-w
Gubert, G. F., Hochrein, S. M., Sinning, K., & Vaeth, M. . (2025). Metabolic Screening of T Lymphocytes During Activation via SEAHORSE Extracellular Flux (XF) Analysis. In N. J. Clifton (Ed.), Methods in molecular biology (Vol. 2904, pp. 243–258). https://doi.org/10.1007/978-1-0716-4414-0_17
Faris, R., Koch, R., McCaslin, P., Challagundla, N., Steiert, B., Andersen, S. E., Smith, P., Jabeena, C. A., Yau, P., Rudel, T., & Weber, M. M. (2025). The Chlamydia trachomatis secreted effector protein CT181 binds to Mcl-1 to prolong neutrophil survival. mBio. https://doi.org/10.1101/2025.03.16.643443, The Chlamydia trachomatis secreted effector protein CT181 binds to Mcl-1 to prolong neutrophil survival
Freitag, A., Gunther, K., Campillo Prados, M., Hochrein, S. M., Schmitz, W., Sinning, K., Zischinsky, G., Klebl, B., Ohlsen, K., Morschhauser, J., Werz, O., Jordan, P. M., & Vaeth, M. (2025). Glucose metabolism controls oxidative burst and lipid mediator production in neutrophils upon microbial challenge. Microlife, 6, uqaf040. https://doi.org/10.1093/femsml/uqaf040
Guo, Y., Stulz, S. V., Kessie, D. K., Vollmuth, N., Torcellan, T., Knobeloch, K. P., Gasteiger, G., & Rudel, T. (2025). Secreted ISG15 induced by Chlamydia trachomatis infection exerts immunomodulatory effects on IFN-gamma defense and inflammation. PLoS Pathog, 21(7), e1013315. https://doi.org/10.1371/journal.ppat.1013315
Heilig, L., Bussemer, L., Strobel, L., Hunniger-Ast, K., Kurzai, O., Grothey, A., Dolken, L., Laib Sampaio, K., Panagiotou, G., Westermann, A. J., Einsele, H., Wurster, S., Schauble, S., & Loffler, J. (2025). Unveiling immune interference: how the dendritic cell response to co-infection with Aspergillus fumigatus is modulated by human cytomegalovirus and its virokine (CMV)IL-10. mBio, 16(11), e0154125. https://doi.org/10.1128/mbio.01541-25
Jobin, K., Seetharama, D., Ruttger, L., Fenton, C., Kharybina, E., Wirsching, A., Huang, A., Knopper, K., Kaisho, T., Busch, D. H., Vaeth, M., Saliba, A. E., Graw, F., Pulfer, A., Gonzalez, S. F., Zehn, D., Liang, Y., Ugur, M., Gasteiger, G., & Kastenmuller, W. (2025). A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals. Science, 388(6743), eadq1405. https://doi.org/10.1126/science.adq1405
Karta, J., Meyers, M., Rodriguez, F., Koncina, E., Gilson, C., Klein, E., Gabola, M., Benzarti, M., Perez Escriva, P., Molina Tijeras, J. A., Correia Tavares Bernardino, C., Ponath, F., Carpentier, A., Pujabet, M. A., Schmoetten, M., Tsenkova, M., Saoud, P., Gaigneaux, A., Ternes, D.,…Letellier, E. (2025). Fusobacterium nucleatum interacts with cancer-associated fibroblasts to promote colorectal cancer. EMBO J, 44(19), 5375-5393. https://doi.org/10.1038/s44318-025-00542-w
Lange, M., Korte, A., Fuchs, M., Fekete, A., Mueller, C., Dierich, B., Witte, J., Dandekar, T., Mueller, M. J., & Berger, S. (2025). A CW-type zinc finger protein is involved in RES-oxylipin signaling and the response to abiotic stress in Arabidopsis thaliana. Front Plant Sci, 16, 1535643. https://doi.org/10.3389/fpls.2025.1535643
Luqman, A., & Ohlsen, K. (2025). Cytokine-mediated inhibition of Staphylococcus aureus adherence and invasion into nonphagocytic cells. Med Microbiol Immunol, 214(1), 31. https://doi.org/10.1007/s00430-025-00840-4
Man, K., Duarte da Silva, V. A., Potemkin, N., Gabriel, S. S., Mason, T., Elmzzahi, T., De Lima Moreira, M., Su, C. H., Mackay, L., Beyer, M. D., Schroder, J., Gasteiger, G., & Kallies, A. (2025). Stem-like tissue-resident memory T cells control functional heterogeneity and reactivation of T cell memory in the intestine. Sci Immunol, 10(112), eadw1992. https://doi.org/10.1126/sciimmunol.adw1992
Moldovan, A., Flannagan, R. S., Ruhling, M., Stelzner, K., Hans, C., Paprotka, K., Kunz, T. C., Heinrichs, D. E., Rudel, T., & Fraunholz, M. J. (2025). Inactivation of branched-chain amino acid uptake halts Staphylococcus aureus growth and induces bacterial quiescence within macrophages. PLoS Pathog, 21(8), e1013291. https://doi.org/10.1371/journal.ppat.1013291
Neyazi, M., Samperio Ventayol, P., Burkard, N., Schlegel, N., Aguilar, C., & Bartfeld, S. (2025). Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid-derived monolayers compared to HeLa cells. FEBS Lett. https://doi.org/10.1002/1873-3468.70182
Osmanoglu, O., Ozer, E., Gupta, S. K., Heinze, K. G., Schulze, H., & Dandekar, T. (2025). Network Controllability Reveals Key Mitigation Points for Tumor-Promoting Signaling in Tumor-Educated Platelets. Int J Mol Sci, 26(21). https://doi.org/10.3390/ijms262110780
Pirr, S., Willers, M., & Viemann, D. (2025). The neonate respiratory microbiome. Acta Physiol (Oxf), 241(2), e14266. https://doi.org/10.1111/apha.14266
Prakash, P. G., Kumar, N., Koster, S., Wentland, C., Dhanraj, J., Gurumuthy, R. K., & Chumduri, C. (2025). Single-cell atlas of cervical organoids uncovers epithelial immune heterogeneity and intercellular cross-talk during Chlamydia infection. Sci Adv, 11(40), eady1640. https://doi.org/10.1126/sciadv.ady1640
Salihoglu, R., Nieves, J., Dandekar, G., Ebert, R., Rudert, M., Dandekar, T., & Bencurova, E. (2025). Machine learning and gene network integration reveal prognostic subnetworks and biomarkers in pancreatic cancer. Comput Struct Biotechnol J, 27, 4151-4162. https://doi.org/10.1016/j.csbj.2025.09.028
Sinning, K., Hochrein, S. M., Gubert, G. F., & Vaeth, M. (2025). Metabolic Profiling of Activated T Lymphocytes Using Single-Cell Energetic Metabolism by Profiling Translation Inhibition (SCENITH). Methods Mol Biol, 2904, 259-271. https://doi.org/10.1007/978-1-0716-4414-0_18
Stulz, S., & Gasteiger, G. (2025). Resident memory T cells call the shots in tissue immunity. Immunity, 58(10), 2364-2366. https://doi.org/10.1016/j.immuni.2025.09.017
Wu H, P. M., Vaeth M. (2025). Metabolic Regulation of T Cell Exhaustion. Immune Discovery, 1(10005). https://doi.org/10.70322/immune.2025.10005
Yin, C., Fedorov, A., Guo, H., Crawford, J. C., Rousseau, C., Zhong, X., Williams, R. M., Gautam, A., Koehler, H. S., Whisnant, A. W., Hennig, T., Rozina, A., Zhong, Y., Lv, S., Bergant, V., Wang, S., Droge, P., Miller, S., Poptsova, M.,…Balachandran, S. (2025). Host cell Z-RNAs activate ZBP1 during virus infections. Nature, 648(8094), 707-716. https://doi.org/10.1038/s41586-025-09705-5
2024
Agrawal, A., Thomann, S., Basu, S., & Grun, D. (2024). NiCo identifies extrinsic drivers of cell state modulation by niche covariation analysis. Nat Commun, 15(1), 10628. https://doi.org/10.1038/s41467-024-54973-w
Akash, A., Bencurova, E., & Dandekar, T. (2024). How to make DNA data storage more applicable. Trends Biotechnol, 42(1), 17-30. https://doi.org/10.1016/j.tibtech.2023.07.006
Balkenhol, J., Handel, B., Biswas, S., Grohmann, J., Kistowski, J. V., Prada, J., Bosman, C. A., Ehrenreich, H., Wojcik, S. M., Kounev, S., Blum, R., & Dandekar, T. (2024). Beyond-local neural information processing in neuronal networks. Comput Struct Biotechnol J, 23, 4288-4305. https://doi.org/10.1016/j.csbj.2024.10.040
Batliner, M., Schumacher, F., Wigger, D., Vivas, W., Prell, A., Fohmann, I., Kohler, T., Schempp, R., Riedel, A., Vaeth, M., Fekete, A., Kleuser, B., Kurzai, O., & Nieuwenhuizen, N. E. (2024). The Candida albicans quorum-sensing molecule farnesol alters sphingolipid metabolism in human monocyte-derived dendritic cells. mBio, 15(8), e0073224. https://doi.org/10.1128/mbio.00732-24
Berg, K., Lodha, M., Delazer, I., Bartosik, K., Garcia, Y. C., Hennig, T., Wolf, E., Dolken, L., Lusser, A., Prusty, B. K., & Erhard, F. (2024). Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data. Nucleic Acids Research, 52(7), e35. https://doi.org/10.1093/nar/gkae120
Castelo, J., Araujo-Aris, S., Barriales, D., Tanner Pasco, S., Seoane, I., Pena-Cearra, A., Palacios, A., Simo, C., Garcia-Canas, V., Khamwong, M., Martin-Ruiz, I., Gonzalez-Lopez, M., Barcena, L., Martin Rodriguez, J. E., Lavin, J. L., Gutiez, N., Marcos, R., Atondo, E., Cobela, A.,…Rodriguez, H. (2024). The microbiota metabolite, phloroglucinol, confers long-term protection against inflammation. Gut Microbes, 16(1), 2438829. https://doi.org/10.1080/19490976.2024.2438829
Costa, B., Becker, J., Krammer, T., Mulenge, F., Duran, V., Pavlou, A., Gern, O. L., Chu, X., Li, Y., Cicin-Sain, L., Eiz-Vesper, B., Messerle, M., Dolken, L., Saliba, A. E., Erhard, F., & Kalinke, U. (2024). Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells. Nat Commun, 15(1), 1745. https://doi.org/10.1038/s41467-024-45614-3
Crouch, S. A. W., Krause, J., Dandekar, T., & Breitenbach, T. (2024). DataXflow: Synergizing data-driven modeling with best parameter fit and optimal control - An efficient data analysis for cancer research. Comput Struct Biotechnol J, 23, 1755-1772. https://doi.org/10.1016/j.csbj.2024.04.010
Cruz de Casas, P., Knopper, K., Dey Sarkar, R., & Kastenmuller, W. (2024). Same yet different - how lymph node heterogeneity affects immune responses. Nat Rev Immunol, 24(5), 358-374. https://doi.org/10.1038/s41577-023-00965-8
Goldmann, O., Nwofor, O. V., Chen, Q., & Medina, E. (2024). Mechanisms underlying immunosuppression by regulatory cells. Front Immunol, 15, 1328193. https://doi.org/10.3389/fimmu.2024.1328193
Gunther, K., Nischang, V., Cseresnyes, Z., Kruger, T., Sheta, D., Abboud, Z., Heinekamp, T., Werner, M., Kniemeyer, O., Beilhack, A., Figge, M. T., Brakhage, A. A., Werz, O., & Jordan, P. M. (2024). Aspergillus fumigatus-derived gliotoxin impacts innate immune cell activation through modulating lipid mediator production in macrophages. Immunology, 173(4), 748-767. https://doi.org/10.1111/imm.13857
Gurumurthy, R. K., Kumar, N., & Chumduri, C. (2024). Culturing and Differentiation of Patient-Derived Ectocervical Epithelial Stem Cells Using Air-Liquid Interphase and Matrigel Scaffold. Methods Mol Biol, 2749, 109-121. https://doi.org/10.1007/978-1-0716-3609-1_11
Hartmann, C. R., Khan, R., Schöning, J., Richter, M., Willers, M., Pirr, S., Heckmann, J., Dirks, J., Morbach, H., Konrad, M., Fries, E., Winkler, M., Büchel, J., Seidenspinner, S., Fischer, J., Vollmuth, C., Meinhardt, M., Marissen, J., Schmolke, M.,…Viemann, D. (2024). A clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI) [Clinical Trial]. Frontiers in Immunology, Volume 15 - 2024. https://doi.org/10.3389/fimmu.2024.1443665
Hovhannisyan, P., Stelzner, K., Keicher, M., Paprotka, K., Neyazi, M., Pauzuolis, M., Ali, W. M., Rajeeve, K., Bartfeld, S., & Rudel, T. (2024). Infection of human organoids supports an intestinal niche for Chlamydia trachomatis. PLoS Pathog, 20(8), e1012144. https://doi.org/10.1371/journal.ppat.1012144
Kumar, N., Prakash, P. G., Wentland, C., Kurian, S. M., Jethva, G., Brinkmann, V., Mollenkopf, H. J., Krammer, T., Toussaint, C., Saliba, A. E., Biebl, M., Jurgensen, C., Wiedenmann, B., Meyer, T. F., Gurumurthy, R. K., & Chumduri, C. (2024). Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis. Nat Commun, 15(1), 3064. https://doi.org/10.1038/s41467-024-47173-z
Leon-Lara, X., Fichtner, A. S., Willers, M., Yang, T., Schaper, K., Riemann, L., Schoning, J., Harms, A., Almeida, V., Schimrock, A., Janssen, A., Ospina-Quintero, L., von Kaisenberg, C., Forster, R., Eberl, M., Richter, M. F., Pirr, S., Viemann, D., & Ravens, S. (2024). gammadelta T cell profiling in a cohort of preterm infants reveals elevated frequencies of CD83+ gammadelta T cells in sepsis. J Exp Med, 221(7). https://doi.org/10.1084/jem.20231987
Perruzza, L., Heckmann, J., Rezzonico Jost, T., Raneri, M., Guglielmetti, S., Gargari, G., Palatella, M., Willers, M., Fehlhaber, B., Werlein, C., Vogl, T., Roth, J., Grassi, F., & Viemann, D. (2024). Postnatal supplementation with alarmins S100a8/a9 ameliorates malnutrition-induced neonate enteropathy in mice. Nat Commun, 15(1), 8623. https://doi.org/10.1038/s41467-024-52829-x
Rasbach, L., Caliskan, A., Saderi, F., Dandekar, T., & Breitenbach, T. (2024). An orchestra of machine learning methods reveals landmarks in single-cell data exemplified with aging fibroblasts. PLoS One, 19(4), e0302045. https://doi.org/10.1371/journal.pone.0302045
Rühling, M., Kersting, L., Wagner, F., Schumacher, F., Wigger, D., Helmerich, D. A., Pfeuffer, T., Elflein, R., Kappe, C., Sauer, M., Arenz, C., Kleuser, B., Rudel, T., Fraunholz, M., & Seibel, J. (2024). Trifunctional sphingomyelin derivatives enable nanoscale resolution of sphingomyelin turnover in physiological and infection processes via expansion microscopy. Nat Commun, 15(1), 7456. https://doi.org/10.1038/s41467-024-51874-w
Rühling, M., Schmelz, F., Ulbrich, K., Schumacher, F., Wolf, J., Pfefferle, M., Priester, M., Moldovan, A., Knoch, N., & Iwanowitsch, A. (2024). A novel rapid host cell entry pathway determines intracellular fate of Staphylococcus aureus. eLife, 13: RP102810. https://doi.org/10.7554/eLife.102810.4
Salihoglu, R., Balkenhol, J., Dandekar, G., Liang, C., Dandekar, T., & Bencurova, E. (2024). Cat-E: A comprehensive web tool for exploring cancer targeting strategies. Comput Struct Biotechnol J, 23, 1376-1386. https://doi.org/10.1016/j.csbj.2024.03.024
Torcellan, T., Friedrich, C., Doucet-Ladeveze, R., Ossner, T., Sole, V. V., Riedmann, S., Ugur, M., Imdahl, F., Rosshart, S. P., Arnold, S. J., Gomez de Aguero, M., Gagliani, N., Flavell, R. A., Backes, S., Kastenmuller, W., & Gasteiger, G. (2024). Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection. Immunity, 57(1), 124-140 e127. https://doi.org/10.1016/j.immuni.2023.11.018
Wang, W., Wang, Y., Lyu, R., & Grun, D. (2024). Scalable identification of lineage-specific gene regulatory networks from metacells with NetID. Genome Biol, 25(1), 275. https://doi.org/10.1186/s13059-024-03418-0
2023
Caliskan, A., Caliskan, D., Rasbach, L., Yu, W., Dandekar, T., & Breitenbach, T. (2023). Optimized cell type signatures revealed from single-cell data by combining principal feature analysis, mutual information, and machine learning. Comput Struct Biotechnol J, 21, 3293-3314. https://doi.org/10.1016/j.csbj.2023.06.002
Caliskan, A., Dangwal, S., & Dandekar, T. (2023). Metadata integrity in bioinformatics: Bridging the gap between data and knowledge. Comput Struct Biotechnol J, 21, 4895-4913. https://doi.org/10.1016/j.csbj.2023.10.006
Hader, A., Schauble, S., Gehlen, J., Thielemann, N., Buerfent, B. C., Schuller, V., Hess, T., Wolf, T., Schroder, J., Weber, M., Hunniger, K., Loffler, J., Vylkova, S., Panagiotou, G., Schumacher, J., & Kurzai, O. (2023). Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity. Nat Commun, 14(1), 3239. https://doi.org/10.1038/s41467-023-38994-5
Hung, S., Kasperkowitz, A., Kurz, F., Dreher, L., Diessner, J., Ibrahim, E. S., Schwarz, S., Ohlsen, K., & Hertlein, T. (2023). Next-generation humanized NSG-SGM3 mice are highly susceptible to Staphylococcus aureus infection. Front Immunol, 14, 1127709. https://doi.org/10.3389/fimmu.2023.1127709
Osmanoglu, O., Gupta, S. K., Almasi, A., Yagci, S., Srivastava, M., Araujo, G. H. M., Nagy, Z., Balkenhol, J., & Dandekar, T. (2023). Signaling network analysis reveals fostamatinib as a potential drug to control platelet hyperactivation during SARS-CoV-2 infection. Front Immunol, 14, 1285345. https://doi.org/10.3389/fimmu.2023.1285345
Salihoglu, R., Srivastava, M., Liang, C., Schilling, K., Szalay, A., Bencurova, E., & Dandekar, T. (2023). PRO-Simat: Protein network simulation and design tool. Comput Struct Biotechnol J, 21, 2767-2779. https://doi.org/10.1016/j.csbj.2023.04.023
Wu, H., Zhao, X., Hochrein, S. M., Eckstein, M., Gubert, G. F., Knopper, K., Mansilla, A. M., Oner, A., Doucet-Ladeveze, R., Schmitz, W., Ghesquiere, B., Theurich, S., Dudek, J., Gasteiger, G., Zernecke, A., Kobold, S., Kastenmuller, W., & Vaeth, M. (2023). Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1alpha-mediated glycolytic reprogramming. Nat Commun, 14(1), 6858. https://doi.org/10.1038/s41467-023-42634-3